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The most commonly reported side effects were mild and included headache, minor gastrointestinal disturbances (flatulence, mild diarrhea at high doses), upper respiratory symptoms, and mild injection site reactions

The committee also voted in favor of MOTS-C and TB-500

In practical terms, they act as chemical messengers: they bind to receptors on cells, interact directly with proteins, or prompt the body to release a specific hormone, then let that hormone carry out the actual work

Emerging pharmacotherapies for obesity: A systematic review

Hyposecretion of fluid from tracheal submucosal glands of CFTR-deficient pigs